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303 Moreover, hepatic iron accumulation can induce the transcription expression of ACSL4 by activating the transcription factor c-Myc, and further aggravate the development of MASH through ferroptosis

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Nature 560 , 649654 (2018)

Apoptosis, or programmed cell death, is a cellular mechanism that eliminates injured and infected cells or those that have reached the end of their lifespan 75